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Organs on Ice: The Future of Transplantation

Could supercooling and cryopreservation one day revolutionise organ donation?

Researchers are making strides in preserving organs outside the body, aiming to extend their viability far beyond the current few hours. Techniques like supercooling and cryopreservation hold promise for creating organ banks that could transform transplant waiting times.


The breakthroughs include studies where pig kidneys were successfully supercooled and reimplanted after days of storage at −4 °C, marking a significant step towards longer-term preservation. While freezing human organs has proven challenging due to ice crystal damage, efforts continue with the hope of someday thawing stored organs for transplantation.


Other methods, such as machine perfusion, provide nutrients to mimic natural conditions, extending organ viability even further. These advancements could not only save more lives but also offer a chance for better matches and less urgent surgeries.


The journey towards cryopreservation is fraught with complexities, from ensuring cell survival during freezing to the ethical considerations of long-term storage. Yet, the potential benefits are immense, making this field one to watch closely in the years ahead.

Original source:  https://www.technologyreview.com/2026/07/24/1140790/the-quest-to-keep-organs-alive-outside-the-body/
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